Cyclopentolate Online



How and where to order Cyclopentolate Hydrochloride (Cyclogyl) 1% 5 ml ophthalmic solution online on American Board of Clinical Optometry website:

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Prices:from $6.16 per bottle
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Forms:Cyclopentolate HCl 1% 5 ml eye drops
Quantity:1-6 bottles
Type:Cyclopentolate brand, Cyclogyl generic
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Cyclopentolate (trade names include Cyclogyl, Ciclolux, Ciclopentolato, Cicloplegico, Colircusi Cicloplejico, Cyclomed, Cyclopent, Cyclopentolat Alcon, Minims Cyclopentolate) is an ophthalmological mydriatic and cycloplegic medication from anticholinergics pharmacological group. This medicine is used during eye examinations that dilates the eye (mydriatic), prevents accommodation of the eye to different distances (cycloplegic). It is usually indicated for diagnostic procedures. Cyclopentolate (Cyclogyl) is also prescribed as an atropine substitute to reverse muscarinic and CNS effects of indirect cholinomimetic (anti-AChase) administration.


Cyclogyl (Cyclopentolate Hydrochloride) ophthalmic solution 1%


Related medications:

  • Apraclonidine (Iopidine)
  • Atropine (Atropisol)
  • Azelastine (Optivar)
  • Bimatoprost (Careprost, Latisse, Lumigan)
  • Brimonidine (Alphagan)
  • Ciprofloxacin (Ciloxan)
  • Clonidine (Catapres)
  • Cyclopentolate, Phenylephrine (Cyclomydril)
  • Dipivefrine (Propine)
  • Dorzolamide, Timolol Maleate (Cosopt)
  • Epinephrine (Anapen)
  • Epinephrine Hydrogen Tartrate, Pilocarpine Hydrochloride (Epilo)
  • Homatropine (Homat)
  • Ketorolac (Acular)
  • Latanoprost (Xalatan)
  • Levobunolol (Betagan)
  • Loteprednol (Lotemax)
  • Methylscopolamine (Methscopolamine)
  • Minoxidil (Rogaine)
  • Ofloxacin (Ocuflox)
  • Phenylephrine, Tropicamide (Mydrin-P)
  • Scopolamine (Isopto Hyoscine)
  • Timolol (Timoptic)
  • Tropicamide (Mydriacyl)


    Pharmacological and medical categories:

  • Cycloplegics
  • Eye care medications
  • Mydriatics
  • Muscle relaxants
  • Ophthalmic preparations


    ATC codes:

  • S - Sensory organs
  • S01 - Ophthalmologicals
  • S01F - Mydriatics and cycloplegics
  • S01FA - Anticholinergics
  • S01FA04 - Cyclopentolate


    ICD-10 codes:

  • Disorders of ocular muscles, binocular movement, accommodation and refraction - H49-H52
  • Disorders of refraction and accommodation - H52
  • Encounter for other special examination without complaint, suspected or reported diagnosis - Z01
  • Encounter for examination of eyes and vision without abnormal findings - Z01.00


    Indications and usage:

    Cyclogyl (Cyclopentolate Hydrochloride) ophthalmic solution is used to produce mydriasis and cycloplegia.


    Dosage and administration:

    Adults

    Instill one or two drops of 0.5%, 1% or 2% solution in the eye which may be repeated in five to ten minutes if necessary. Complete recovery usually occurs in 24 hours. Complete recovery from mydriasis in some individuals may require several days.

    Children

    Instill one or two drops of 0.5%, 1% or 2% solution in the eye which may be repeated five to ten minutes later by a second application of 0.5% or 1% solution if necessary.

    Small Infants

    A single instillation of one drop of 0.5% in theeye. To minimize absorption, apply pressure over the nasolacrimal sac for two to three minutes. Observe infant closely for at least 30 minutes following instillation. Individuals with heavily pigmented irides may require higher strengths.


    Dosage forms and strengths:

    Cyclogyl (Cyclopentolate Hydrochloride) eye drops 0.5%, 1%, 2% in multiple-dose plastic dispensers 2 ml, 5 ml, 15 ml.


    Overdosage:

    Excessive dosage may produce behavioral disturbances, tachycardia, hyperpyrexia, hypertension, elevated intraocular pressure, vasodilation, urinary retention, diminished gastrointestinal motility and decreased secretion in salivary and sweat glands, pharynx, bronchi and nasal passages. Patients exhibiting signs of overdosage should receive supportive care and monitoring.


    Contraindications:

    Ophthalmic Cyclopentolate HCl should not be used when untreated narrow-angle glaucoma, or untreated anatomically narrow angles are present, or if the patient is hypersensitive to any component of this medication.


    Warnings:

    Cyclogyl (Cyclopentolate HCl) eye drops is for topical ophthalmic use only, not for injection. This medication may cause CNS disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate. To minimize absorption, use only 1 drop of 0.5% Cyclogyl solution per eye, followed by pressure applied over the nasolacrimal sac for two to three minutes. Observe infants closely for at least 30 minutes following instillation.

    Mydriatics may produce a transient elevation of intraocular pressure.


    Precautions:

    The lacrimal sac should be compressed by digital pressure for two to three minutes after instillation to reduce excessive systemic absorption. Caution should be observed when considering use of this medication in the presence of Down's syndrome and in those predisposed to angle-closure glaucoma.


    Side effects, adverse reactions:

    Ocular

    Most common adverse reactions of Cyclogyl eye drops are increased intraocular pressure, burning, photophobia, blurred vision, irritation, hyperemia, conjunctivitis, blepharoconjunctivitis, punctate keratitis, synechiae.

    Non-ocular

    Use of cyclopentolate has been associated with psychotic reactions and behavioral disturbances, usually in children, especially with 2% concentration. These disturbances include ataxia, incoherent speech, restlessness, hallucinations, hyperactivity, seizures, disorientation as to time and place, and failure to recognize people. This drug produces reactions similar to those of other anticholinergic drugs, but the central nervous system manifestations as noted above are more common. Other toxic manifestations of anticholinergic drugs are skin rash, abdominal distention in infants, unusual drowsiness, tachycardia, hyperpyrexia, vasodilation, urinary retention, diminished gastrointestinal motility and decreased secretion in salivary and sweat glands, pharynx, bronchi and nasal passages. Severe manifestations of toxicity include coma, medullary paralysis and death.


    Drug interactions:

    Cyclopentolate (Cyclogyl) may interfere with the ocular anti-hypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.


    Use in specific populations:

    Pregnancy

    Animal reproduction studies have not been conducted with cyclopentolate. It is also not known whether cyclopentolate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Cyclogyl should be administered to a pregnant woman only if clearly needed.

    Nursing mothers

    It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when cyclopentolate hydrochloride is administered to a nursing woman.

    Pediatric use

    Use of Cyclogyl has been associated with psychotic reactions and behavioral disturbances in pediatric patients. Increased susceptibility to cyclopentolate has been reported in infants, young children, and in children with spastic paralysis or brain damage. These disturbances include ataxia, incoherent speech, restlessness, hallucinations, hyperactivity, seizures, disorientation as to time and place, and failure to recognize people. Feeding intolerance may follow ophthalmic use of this product in infants. It is recommended that feeding be withheld for four hours after examination. Observe infants closely for at least 30 minutes.

    Geriatric use

    No overall differences in safety or effectiveness have been observed between elderly and younger patients.


    Information for patients:

  • Do not touch dropper tip to any surface, as this may contaminate the solution.
  • A transient burning sensation may occur upon instillation.
  • Patients should be advised not to drive or engage in other hazardous activities while pupils are dilated.
  • Patients may experience sensitivity to light and should protect eyes in bright illumination during dilation.
  • Parents should be warned not to get this preparation in their child's mouth and to wash their own hands and the child's hands following administration.
  • Feeding intolerance may follow ophthalmic use of this product in infants. It is recommended that feeding be withheld for four hours after examination.


    Pregnancy categories:

  • B2 - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other forms:

  • Cyclopentolate Base
  • Cyclopentolate Hydrochloride


    Synonyms, international and chemical names:

  • Ciclopentolato
  • Ciklopentolat
  • Cloridrato de Ciclopentolato
  • Cyclopentoiate
  • Cyclopentol HCL
  • Cyclopentolaat
  • Cyclopentolat
  • Cyclopentolate HCl
  • Cyclopentolati
  • Cyclopentolatum
  • Cyclopentylate
  • Syklopentolaatti


    Brands, generics, trade names:

  • AK-Pentolate - Akorn
  • Ciclolux - Allergan
  • Ciclopegic - Llorens
  • Ciclopenal - Alcon
  • Ciclopentolato - Oftalmoquimica
  • Cicloplegico - Allergan
  • Cicloplejico - Alcon
  • Colircusi Cicloplejico - Alcon
  • Cyclogyl - Alcon, Intas Pharmaceuticals, Novartis
  • Cyclomed - Promed Exports
  • Cyclomydri - Alcon
  • Cyclopent - Sun Pharmaceutical Industries
  • Cyclopentolat - Alcon
  • Cyclopentolate - Akorn, Alcon
  • Cylate - CYNACON / OCuSOFT
  • Minims Cyclopentolate - Chauvin Pharmaceuticals, Apex Pharma, Bausch and Lomb, U.S. Summit, Valeant Pharmaceuticals
  • Mydrilate - Intrapharm Laboratories, United Drug
  • Pentolate - Sunways India
  • Skiacol - Alcon
  • Zyklolat-EDO - Dr. Gerhard Mann


    APIs used in medicine in combinations with cyclopentolate:

  • Dexamethasone
  • Lidocaine
  • Naphazoline
  • Phenylephrine
  • Phenylmercuric Nitrate


    Here is a list of popular medications containing cyclopentolate as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Colircusi Cicloplejico
  • Drops; Ophthalmic; Cyclopentolate Hydrochloride 1%
  • Alcon
  • Summit
  • Cyclogyl
  • Solution; Ophthalmic; Cyclopentolate Hydrochloride 0.5%
  • Solution; Ophthalmic; Cyclopentolate Hydrochloride 1%
  • Solution; Ophthalmic; Cyclopentolate Hydrochloride 2%
  • Alcon
  • Andre Laboratories
  • DKSH
  • Firma Chun Cheong
  • Intas Pharmaceuticals
  • Novartis
  • Summit
  • Cyclopent
  • Drops; Ophthalmic; Cyclopentolate Hydrochloride 1%
  • Sun Pharmaceutical Industries
  • Milmet Pharma
  • Minims Cyclopentolate
  • Solution; Ophthalmic; Cyclopentolate Hydrochloride 0.5%
  • Solution; Ophthalmic; Cyclopentolate Hydrochloride 1%
  • Chauvin Pharmaceuticals
  • Apex Pharma
  • Bausch and Lomb
  • Pan-Malayan Pharmaceuticals
  • Rich Plan International
  • U.S. Summit
  • Valeant Pharmaceuticals
  • Zuellig Pharma



  • References:

  • Cyclopentolate main article on Wikipedia: https://en.wikipedia.org/wiki/Cyclopentolate
  • Cyclopentolate compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Cyclopentolate
  • Cyclopentolate Hydrochloride compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Cyclopentolate-hydrochloride
  • Cyclopentolate medicine on DrugBank: https://go.drugbank.com/drugs/DB00979
  • Cyclopentolate Hydrochloride on DrugBank: https://go.drugbank.com/salts/DBSALT000476
  • Cyclopentolate Ophthalmic FAQ on MedlinePlus (revised 03/15/2016): https://medlineplus.gov/druginfo/meds/a616014.html
  • Cyclopentolate Hydrochloride solution/drops drug label on DailyMed (revised October 8, 2020): https://dailymed.nlm.nih.gov/dailymed/lookup...
  • Cyclogyl (Cyclopentolate Hydrochloride) solution/drops drug label on DailyMed (revised December 21, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Cyclopentolate containing drugs on Drugs-About.com: https://drugs-about.com/ing/cyclopentolate.html
  • Cyclopentolate for sale on Pharma Doctor: https://pharma-doctor.com/cyclopentolate.html
  • Cyclogyl (Cyclopentolate Hydrochloride ophthalmic solution, USP) official prescribing information from Alcon pharmaceutical company (revised October 2015): http://embed.widencdn.net/pdf/plus/alcon/...
  • Cyclogyl (Cyclopentolate Hydrochloride) ophthalmic solution full prescribing information on Drugs.com (revised December 1, 2020): https://www.drugs.com/pro/cyclogyl.html
  • Cyclogyl (Cyclopentolate Hydrochloride) eye drops 1% consumer medicine information on NPS MedicineWise (revised October 2020): https://www.nps.org.au/assets/medicines/...
  • Minims Cyclopentolate Hydrochloride 0.5% and 1% eye drops patient information leaflet from Medicines.org.uk (revised March 2020): https://www.medicines.org.uk/emc/files/pil.3741.pdf

    Revised: June 2021



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